منابع مشابه
Targeted Therapies for Pancreatic Cancer
Pancreatic cancer is the third leading cause of cancer related death and by 2030, it will be second only to lung cancer. We have seen tremendous advances in therapies for lung cancer as well as other solid tumors using a molecular targeted approach but our progress in treating pancreatic cancer has been incremental with median overall survival remaining less than one year. There is an urgent ne...
متن کاملTargeted therapies for pancreatic cancer.
INTRODUCTION Pancreatic cancer is a devastating malignancy and a leading cause of cancer mortality. Furthermore, early diagnosis represents a serious hurdle for clinicians, as symptoms are non-specific and usually manifest in advanced, treatment-resistant stages of the disease. SOURCES OF DATA Here, we review the rationale and progress of targeted therapies currently under investigation. AR...
متن کاملTargeted cancer therapies
With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an o...
متن کاملNetwork systems biology for targeted cancer therapies
The era of targeted cancer therapies has arrived. However, due to the complexity of biological systems, the current progress is far from enough. From biological network modeling to structural/dynamic network analysis, network systems biology provides unique insight into the potential mechanisms underlying the growth and progression of cancer cells. It has also introduced great changes into the ...
متن کاملProgress in Targeted Therapies for Cancer: Overview
Targeted therapies for cancer can be broadly defined as treatments directed against abnormally activated molecules or physiological processes required for maintenance or progression of tumours. In recent years, many targeted therapies have become established in daily clinical practice and a huge number of agents are in various stages of pre-clinical and clinical development. The concept of targ...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2004
ISSN: 0002-9173,1943-7722
DOI: 10.1309/5cwpu41afr1vym3f